In summary, randomized controlled trials that lowered intake of dietary saturated fat and replaced it with polyunsaturated vegetable oil reduced CVD by ≈30%, similar to the reduction achieved by statin treatment. Prospective observational studies in many populations showed that lower intake of saturated fat coupled with higher intake of polyunsaturated and monounsaturated fat is associated with lower rates of CVD and of other major causes of death and all-cause mortality.
Source: Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association | Circulation
Eat more plants. Eat less of this stuff.
For those readers inclined to go deeper there is a link to the full study report on the AHA website link above.
And for readers who want an opposite point of view go to the article below.
Source: Op-Ed: Vegetable Oils, (Francis) Bacon, Bing Crosby, and the AHA | Medpage Today