Using naltrexone to cut back on drinking isn’t new, says Sarah Wakeman, a senior medical director for substance use disorder at Mass General Brigham. The approach dates back to the 1980s with the Sinclair method, which pairs drinking with naltrexone to blunt alcohol’s pleasurable effects. In parts of Europe, Wakeman adds, people have long used […]
More food for thought (but only if you can read and think): In a new essay for The Chronicle Higher Education, university-level literature and writing instructor Tyler Jagt recalls how not a single one of his students could get through an assigned 20-page article, something that he had read “without complaint” as an undergraduate a […]
Abstract from the study Home alone: Remote work, isolation, and mental health – Science 4 Jun 2026 Vol 392, Issue 6802 https://www.science.org/doi/10.1126/science.aec7671 How does remote work affect isolation and mental health? We drew on five nationally representative surveys of American workers (N = 588,322) conducted from 2011 to 2024, omitting the peak pandemic years of […]
Michael Girdley on private equity: The lesson is pretty straightforward. You’re going to go buy a business, and you’re going to look and say, “Where can I cut costs? How can I start to optimize and streamline this?” You can cut fat, but you definitely don’t want to cut muscle, and you don’t want to […]
In her original post, Auken predicted a time, viz. 2030, wherein she would not ‘own anything’, not a car, a house, nor even any clothes. This was because, she explained, all things previously regarded as a ‘product’ would be supplied and available in the future as a ‘service’. As a result, everything that one might […]
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