Persistent Metabolic Adaptation

Sunday 10/6

Straight to the point. My BMI is back in the overweight range. I was hoping for a random uptick with a gradual return to my 173-175 range but it has not happened. I now fluctuate between 177 and 178. Another pound or two and my skinny jeans won’t fit anymore. So the research geek in me took over. I wanted to know why I’m gaining weight after years of keeping my number down. Lack of enough exercise was an obvious reason. But I also felt my metabolism changed (again) so down the rabbit hole I went. The deeper I went the dots starting connecting.

I recall reading somewhere that successful weight loss maintainers changed their diets multiple times in their lifetimes. I found this to be true in my case. Remember The Biggest Loser television show? I found this fascinating study Persistent metabolic adaptation 6 years after “The Biggest Loser” competition https://doi.org/10.1002/oby.21538. Fascinating because the participants with greater long-term weight loss also had greater ongoing metabolic slowing. It appears my metabolism is slowing down not just from age but also from the fact I’ve maintained my weight loss for a long time.

And if this wasn’t bad enough I stumbled upon Metabolic adaptation is associated with a greater increase in appetite following weight loss: a longitudinal studyhttps://doi.org/10.1016/j.ajcnut.2023.10.010. Lose weight. Appetite increases!

The universe opened up her secrets to me. I need to change my diet (again).

Take Home Lesson

Long-term weight loss requires perpetual behavioral adaptation to offset persistent metabolic adaptation.

In plain English, I have to eat less or I’m screwed. Because I already know I’m in the one third category.

About 10 percent of older people living in their own homes do not eat enough and one-third of people over the age of 65 eat too much. More than half of older people in hospitals or nursing homes have malnutrition (poor nutrition or diet). – https://www.healthinaging.org/a-z-topic/nutrition/basic-facts

Drink More Water (another reminder)

Extreme heat is the number-one weather-related cause of death in the U.S., and it kills more people most years than hurricanes, floods and tornadoes combined. Yet research shows that compared with their thinking about dramatic events such as storm surges and wildfires, people tend to feel more uncertain about what to do under the threat of extreme heat and don’t perceive as much personal risk. This mismatch between the reality of the danger and the actions people take to protect themselves extends beyond individual perception to the policy level. Heat risks to human health are not often prioritized in climate mitigation and adaptation plans—if they are factored in at all.

Extreme Heat Is Deadlier Than Hurricanes, Floods and Tornadoes Combined — https://www.scientificamerican.com/article/extreme-heat-is-deadlier-than-hurricanes-floods-and-tornadoes-combined/

Remember The Death of Common Sense?

A 71-year-old Los Angeles man died in California’s Death Valley National Park on Tuesday, likely due to heat, as the afternoon high recorded in the park was 121 degrees, officials said.

Man featured in LA Times story dies in Death Valley amid 121-degree heat — https://www.sfgate.com/bayarea/article/man-collapses-dies-in-death-valley-18211076.php

“It’s a dry heat.”

Steven Curry (the dead guy)

The Death of Common Sense

What could possibly go wrong?

How and What to Eat to Live to 92! (the Warren Buffett diet)

The famed investor and Berkshire Hathaway CEO counts burgers, hot dogs, and ice cream among his favorite foods. He munches on McDonald’s for breakfast, guzzles five cans of Coke every day, and demolishes cookies and chocolates.

“I checked the actuarial tables, and the lowest death rate is among 6-year-olds. So I decided to eat like a 6-year-old. It’s the safest course I can take.”

Warren Buffett eats McDonald’s for breakfast, drinks 5 Cokes a day, and devours cookies and ice cream — https://markets.businessinsider.com/news/stocks/warren-buffett-diet-mcdonalds-coke-junk-food-soda-ice-cream-2023-4

Genetically Modified Pig OK to Eat

“It shouldn’t have been approved until they had adequately addressed the allergenicity of the product,” said Jaydee Hanson, policy director for the Center for Food Safety.

FDA approved its first GM pig for consumption, potentially safe for red meat allergy sufferers — https://thecounter.org/fda-approves-first-gm-pig-galsafe-red-meat-allergy/

What’s in that sausage?

Frankenpig. This too shall be placed on my Never to Eat List along with…

Genetically engineered salmon goes on sale for the first time – New Scientist

Social Distance and Dine With Mannequins at This Michelin-Starred Restaurant — VinePair

Walking backstage at a theater, in a toy store, or even in a hair salon, it’s not uncommon to come across costumed mannequins. Now, it won’t be uncommon to see the lifelike dolls in some restaurants either. In an effort to get creative amidst cautious restaurant reopenings, a Michelin-starred restaurant in Virginia is adding mannequin…

via Social Distance and Dine With Mannequins at This Michelin-Starred Restaurant — VinePair

Uh… no thanks.