Tag: Mice abuse

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Eat Ice Cream With NO Guilt

Sugar-Free Diet Linked to Metabolic Changes

“Completely removing sucrose from a low-fat diet may unexpectedly disrupt gut health and promote inflammation and metabolic dysfunction, highlighting that balanced nutrition is more important than simply eliminating sugar,” said Rasheed Ahmad, Ph.D., principal scientist and head of the Immunology & Microbiology Department at the Dasman Diabetes Institute, in Kuwait City, Kuwait

To evaluate the effects of eliminating sucrose, the researchers measured glucose tolerance, insulin sensitivity, circulating metabolic hormones, the gut microbiome, and inflammation in both the colon and liver.

Despite maintaining similar body weights, mice on the sucrose-free diet experienced several negative health changes compared with the control group. These included poorer glucose control, insulin resistance, imbalances in gut microbes, intestinal inflammation, and changes associated with fatty liver disease. Scientists found a surprising problem with sugar-free diets – https://www.sciencedaily.com/releases/2026/06/260614011843.htm The Endocrine Society. “Scientists found a surprising problem with sugar-free diets.” ScienceDaily (accessed June 14, 2026).

Today, we eat ice cream!

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Researchers Find Brain Cells That Tell You To Stop Eating (in mice)

“These neurons are unlike any other neuron involved in regulating satiation,” says Alexander Nectow, a physician-scientist at Columbia University Vagelos College of Physicians and Surgeons, who led the research with Srikanta Chowdhury, an associate research scientist in the Nectow lab. “Other neurons in the brain are usually restricted to sensing food put into our mouth, or how food fills the gut, or the nutrition obtained from food. The neurons we found are special in that they seem to integrate all these different pieces of information and more.”

“Essentially these neurons can smell food, see food, feel food in the mouth and in the gut, and interpret all the gut hormones that are released in response to eating,” Nectow says. “And ultimately, they leverage all of this information to decide when enough is enough.”Columbia University Irving Medical Center. “Researchers discover the brain cells that tell you to stop eating.” ScienceDaily. http://www.sciencedaily.com/releases/2025/02/250205131107.htm (accessed February 8, 2025).

I need more of these brain cells.

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Eat Broccoli, Protect Your Gut

Broccoli is known to be beneficial to our health. For example, research has shown that increased consumption of the cruciferous vegetable decreases incidence of cancer and type 2 diabetes. In a recent study, researchers found that broccoli contains certain molecules that bind to a receptor within mice and help to protect the lining of the small intestine, thereby inhibiting the development of disease. The findings lend support to the idea that broccoli truly is a ‘superfood.’

Penn State. “Broccoli consumption protects gut lining, reduces disease, in mice: Researchers discover that a certain molecule in broccoli interacts with a receptor in mice to promote gut health.” ScienceDaily. http://www.sciencedaily.com/releases/2023/04/230406152639.htm (accessed April 9, 2023).
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Sugar disrupts microbiome, eliminates protection against obesity and diabetes (in mice)

Photo by Nishant Aneja on Pexels.com

After four weeks on the diet, the animals showed characteristics of metabolic syndrome, such as weight gain, insulin resistance, and glucose intolerance. And their microbiomes had changed dramatically, with the amount of segmented filamentous bacteria — common in the gut microbiota of rodents, fish, and chickens — falling sharply and other bacteria increasing in abundance.

Sugar disrupts microbiome, eliminates protection against obesity and diabetes — Columbia University Irving Medical Center. “Sugar disrupts microbiome, eliminates protection against obesity and diabetes.” ScienceDaily. http://www.sciencedaily.com/releases/2022/08/220829194721.htm (accessed September 7, 2022)

Here’s the link to the original study – https://www.cell.com/cell/fulltext/S0092-8674(22)00992-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422009928%3Fshowall%3Dtrue

I’m cleaning up my saved drafts for this blog and apologize up front if I’ve already posted this. But since this post was in my draft folder I’m pretty sure I haven’t already posted this. I need to delete some drafts I’ve kept around since 2018.

2018!!!

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