Understanding Your Body’s Defended Fat Mass

Jastreboff’s research focuses on novel anti-obesity medications, specifically nutrient stimulated hormone therapeutics. She believes that a critical need in the field is to better understand obesity pathophysiology, especially how the body signals to the brain how much fat an individual should carry to store sufficient energy to function optimally; this is called the defended fat mass… Jastreboff cites the environment as a cause of obesity, specifically what she and other scientists call the obesogenic environment. “It’s not just the food, it’s not just the fact that we lead fairly sedentary lives,” Jastreboff explained. “It’s the stress, it’s the lack of sleep, it’s the circadian rhythm disruption, it’s things in our obesogenic environment that have led to this elevated defended fat mass on a population level.”

Yale Endocrinology Obesity Medicine: Approaching Obesity as a Complex, Chronic Disease — https://medicine.yale.edu/news-article/yale-endocrinology-obesity-medicine-approaching-obesity-as-a-complex-chronic-disease/

You can now add your body’s defended fat mass to your personal list of reasons why you just can’t lose weight.

I must to go now. Super Bowl pig out starts soon and I have to adjust my defended fat mass set point.

Eat More Protein at Breakfast

A year-long study of the dietary habits of 9,341 Australians has backed growing evidence that highly processed and refined foods are the leading contributor of rising obesity rates in the Western world.

The new study, in the latest issue of the journal Obesity conducted by the University of Sydney’s Charles Perkins Centre (CPC), was based on a national nutrition and physical activity survey undertaken by the Australian Bureau of Statistics (ABS), and further backs the ‘Protein Leverage Hypothesis’. 

Participants with a lower proportion of protein than recommended at the first meal consumed more discretionary foods – energy-dense foods high in saturated fats, sugars, salt, or alcohol – throughout the day, and less of the recommended five food groups (grains; vegetables/legumes; fruit; dairy and meats). Consequently, they had an overall poorer diet at each mealtime, with their percentage of protein energy decreasing even as their discretionary food intake rose – an effect the scientists call ‘protein dilution’. 

“The results support an integrated ecological and mechanistic explanation for obesity, in which low-protein, highly processed foods lead to higher energy intake in response to a nutrient imbalance driven by a dominant appetite for protein,” said Professor Raubenheimer. “It supports a central role for protein in the obesity epidemic, with significant implications for global health.”

Study confirms that processed foods key to rising obesity — https://www.sydney.edu.au/news-opinion/news/2022/11/08/processed-foods-key-to-rising-obesity-study-finds-.html

Beans for breakfast anyone? Eggs?

Link to the original study Macronutrient (im)balance drives energy intake in an obesogenic food environment: An ecological analysis – https://onlinelibrary.wiley.com/doi/10.1002/oby.23578

Earlier posts on the obesogenic food environment:

More on the Obesogenic Environment

Obesogenic food environment